Article
Gene-based single nucleotide polymorphisms and linkage disequilibrium patterns of 29 asthma candidate genes in the chromosome 5q31-33 region in Koreans.
International archives of allergy and immunology - 1 Jan 2006
Ryu Ha-Jung, Jung Ho-Youl, Park Jung-Sun, Ryu Gil-Mi, Heo Jee Yeon, Kim Jae-Jung, Moon Song-Mean, Kim Hung-Tae, Lee Jong-Young, Koh Insong, Kim Jun-Woo, Rho Jae Kyun, Han Bok-Ghee, Kim Hyungtae, Park Choon-Sik, Oh Bermseok, Park Chan, Lee Jong-Keuk, Kimm Kuchan
Abstract excerpt
BACKGROUND AND METHODS: Numerous genetic studies have mapped asthma susceptibility genes to a region on chromosome 5q31-33 in several populations. This region contains a cluster of cytokines and other immune-related genes important in immune response. In the present study, to determine the genetic variations and patterns of linkage disequilibrium (LD), we resequenced all the exons and promoter regions of the 29...
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