Article
SPINK5 and ADRB2 haplotypes are risk factors for asthma in Mexican pediatric patients.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Apr 2015
Martínez-Aguilar N E, Del Río-Navarro B E, Navarro-Olivos E, García-Ortíz H, Orozco L, Jiménez-Morales S
Abstract excerpt
BACKGROUND: Asthma is one of the most common respiratory diseases worldwide, and the complexity of its etiology has been widely documented. Chromosome 5q31-33 is one of the main loci implicated in asthma and asthma-related traits. IL13, CD14 and ADRB2, which are located in this risk locus, are among the genes most strongly associated with asthma susceptibility. OBJECTIVES: This study evaluated whether...
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