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Article

The 5q31 variants associated with psoriasis and Crohn's disease are distinct.

Human molecular genetics - 1 Oct 2008

Li Yonghong, Chang Monica, Schrodi Steven J, Callis-Duffin Kristina P, Matsunami Nori, Civello Daniel, Bui Nam, Catanese Joseph J, Leppert Mark F, Krueger Gerald G, Begovich Ann B

Abstract excerpt

Predisposition to psoriasis is known to be affected by genetic variation in HLA-C, IL12B and IL23R, but other genetic risk factors also exist. We recently reported three psoriasis-associated single nucleotide polymorphisms (SNPs) in the 5q31 locus, a region of high linkage disequilibrium laden with inflammatory pathway genes. The aim of this study was to assess whether other variants in the 5q31 region are causal...

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Identifiers

PMID: 18614543
DOI: 10.1093/hmg/ddn196
PMCID: PMC2536504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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