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Article

Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues.

The Journal of allergy and clinical immunology - 1 Sept 2008

Tremblay Karine, Daley Denise, Chamberland Annie, Lemire Mathieu, Montpetit Alexandre, Laviolette Michel, Musk Arthur W, James Alan L, Chan-Yeung Moira, Becker Allan, Kozyrskyj Anita L, Sandford Andrew J, Hudson Thomas J, Paré Peter D, Laprise Catherine

Abstract excerpt

BACKGROUND: Eight genes in the immune signaling pathway shown to be differentially expressed in asthmatic lung biopsy specimens in a previous microarray experiment were selected as candidate genes for asthma susceptibility. OBJECTIVE: We sought to perform an association study with these genes and asthma-related phenotypes in 3 independent Canadian familial asthma collections and 1 Australian asthma case-control...

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Identifiers

PMID: 18774388
DOI: 10.1016/j.jaci.2008.05.049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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