Article
Age-related changes in lamin A/C expression in the osteoarticular system: laminopathies as a potential new aging mechanism.
Mechanisms of ageing and development - 1 Apr 2006
Duque Gustavo, Rivas Daniel
Abstract excerpt
BACKGROUND: Mutations in lamin A/C have been described as associated to severe changes in bone and joints. In this study we hypothesize that the expression of lamin A/C may play a role in the pathogenesis of age-related diseases in the osteoarticular system. METHODOLOGY: C57BL/6 young and old mic...
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