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Article

A progeroid syndrome in mice is caused by defects in A-type lamins.

Nature - 15 May 2003

Mounkes Leslie C, Kozlov Serguei, Hernandez Lidia, Sullivan Teresa, Stewart Colin L

Abstract excerpt

Numerous studies of the underlying causes of ageing have been attempted by examining diseases associated with premature ageing, such as Werner's syndrome and Hutchinson-Gilford progeria syndrome (HGPS). HGPS is a rare genetic disorder resulting in phenotypes suggestive of accelerated ageing, incl...

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Identifiers

PMID: 12748643
DOI: 10.1038/nature01631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12748643-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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