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Article

Age-related changes in lamin A/C expression in cardiomyocytes.

American journal of physiology. Heart and circulatory physiology - 1 Sept 2007

Afilalo Jonathan, Sebag Igal A, Chalifour Lorraine E, Rivas Daniel, Akter Rahima, Sharma Kamal, Duque Gustavo

Abstract excerpt

Lamin A and C (A/C) are type V intermediate filaments that form the nuclear lamina. Lamin A/C mutations lead to reduced expression of lamin A/C and diverse phenotypes such as familial cardiomyopathies and accelerated aging syndromes. Normal aging is associated with reduced expression of lamin A/C...

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Identifiers

PMID: 17513488
DOI: 10.1152/ajpheart.01194.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17513488-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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