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Article

Klotho: a fundamental regulator of aging.

Ageing research reviews - 1 Sept 2002

Nabeshima Yo-ichi

Abstract excerpt

To escape aging and aging-related disorders has been one of mankind's biggest dreams from the beginning of history. However, our knowledge regarding the molecular mechanisms of aging has been limited. We recently developed a unique short lifespan mouse strain in which a single gene mutation caused multiple aging-related disorders and identified the responsible gene as klotho. The most characteristic phenotypes...

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PMID: 12362891
DOI: 10.1016/s1568-1637(02)00027-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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