Article
A Role of Lamin A/C in Preventing Neuromuscular Junction Decline in Mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 16 Sept 2020
Gao Nannan, Zhao Kai, Cao Yu, Ren Xiao, Jing Hongyang, Xing Guanglin, Xiong Wen-Cheng, Mei Lin
Abstract excerpt
During aging, skeletal muscles become atrophic and lose contractile force. Aging can also impact the neuromuscular junction (NMJ), a synapse that transmits signals from motoneurons to muscle fibers to control muscle contraction. However, in contrast to muscle aging that has been studied extensively, less is known about the molecular mechanisms of NMJ aging although its structure and function are impaired in aged...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.