Article
The Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin and cell surfaces via positively charged amino acids in CCP1-2.
Molecular immunology - 1 Apr 2006
Mark Linda, Lee Wen H, Spiller O Brad, Villoutreix Bruno O, Blom Anna M
Abstract excerpt
The Kaposi's sarcoma-associated herpesvirus (KSHV) complement control protein (KCP) inhibits the human complement system, and is similar in structure and function to endogenous complement inhibitors. Other inhibitors such as C4b-binding protein and factor H, as well as the viral homologue vaccinia virus complement control protein are known to bind heparin and, for the two latter, also to glycosaminoglycans at the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.