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Article

Structure and flexibility of the multiple domain proteins that regulate complement activation

1 Apr 2001

Abstract excerpt

In this review we summarise more than 10 years of biophysical exploration into the structural biology of the regulators of complement activation (RCA). The five human proteins responsible for regulation of the early events of complement are homologous and are composed largely from building blocks called "complement control protein (CCP) modules". Unlike most multiple domain proteins they do not contain any of the...

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PMID: 11414356
DOI: 10.1034/j.1600-065x.2001.1800113.x

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