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Article

2'-MeO-RNA containing oligodeoxyribonucleotide primers can prevent template-independent base extension on microarrays.

Nucleosides, nucleotides & nucleic acids - 1 Jan 2005

Zhao Xiaodong

Abstract excerpt

DNA microarrays require tens of thousands of deoxyoligonucleotides to be registered in an addressable fashion through immobilization, so that they have the high-throughput capability of analyzing a large number of samples simultaneously in a minimal volume of each reagent. However, using immobilized DNA molecules on microarrays can impose certain technical problems for some assays. For example, high background...

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PMID: 16438052
DOI: 10.1080/15257770500268632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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