Article
Hybridization of DNA targets to glass-tethered oligonucleotide probes.
Molecular biotechnology - 1 Dec 1995
Beattie W G, Meng L, Turner S L, Varma R S, Dao D D, Beattie K L
Abstract excerpt
Hybridization of nucleic acids to surface-tethered oligonucleotide probes has numerous potential applications in genome mapping and DNA sequence analysis. In this article, we describe a simple standard protocol for routine preparation of terminal amine-derivatized 9-mer oligonucleotide arrays on...
Topics
- Base Sequence
- Chromosome Mapping
- Cystic Fibrosis Transmembrane Conductance Regulator
- Glass
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Polyethylene Glycols
- Polymerase Chain Reaction
- Sequence Alignment