Article
SNPs analysis by use of oligonucleotides containing 2'-O-methyl-2-thiouridines.
Nucleic acids symposium series (2004) - 1 Jan 2005
Okamoto Itaru, Seio Kohji, Sekine Mitsuo
Abstract excerpt
In this study, we report an improved method for the synthesis of oligonucleotides containing 2-thiouridine (s2U) derivatives. The hybridization affinity and base pair recognition ability of oligonucleotides having 2-thiouracil moieties with both the complementary RNAs and DNAs were also studied in detail. These results indicate that oligonucleotides containing s2U derivatives could be used as powerful tools for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
