Article
Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR.
Pediatric pulmonology - 1 Jul 2011
Yu Jinho, Kang Mi-Jin, Kim Byoung-Ju, Kwon Ji-Won, Song Young-Hwa, Choi Won-Ah, Shin Yee-Jin, Hong Soo-Jong
Abstract excerpt
The gasdermin A (GSDMA) and gasdermin B (GSDMB) genes are located at 17q21.2. The GSDM family genes have been studied in the gastrointestinal tract but recent reports suggest that GSDMB is associated with childhood asthma in several populations. We investigated the association of the GSDMA and GSDMB variants with asthma in Korean children, and to assess the effect of these variants on intermediate phenotypes of...
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