Error detection in SNP data by considering the likelihood of recombinational history implied by three-site combinations.

Abstract excerpt

MOTIVATION: Errors in nucleotide sequence and SNP genotyping data are problematic when inferring haplotypes. Previously published methods for error detection in haplotype data make use of pedigree information; however, for many samples, individuals are not related by pedigree. This article describes a method for detecting errors in haplotypes by considering the recombinational history implied by the patterns of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Cloning, Molecular
• Share to Computational Biology