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Article

Influence of serotonin receptor 2A His452Tyr polymorphism on brain temporal structures: a volumetric MR study.

European journal of human genetics : EJHG - 1 Apr 2006

Filippini Nicola, Scassellati Catia, Boccardi Marina, Pievani Michela, Testa Cristina, Bocchio-Chiavetto Luisella, Frisoni Giovanni B, Gennarelli Massimo

Abstract excerpt

Serotonin (5-HT) receptors 2A are expressed in brain regions involved in memory and learning processes. Recently, a functional single nucleotide polymorphism in the 5-HT2A receptor gene leading to an amino-acid substitution at residue 452 (His452Tyr) has been involved in memory performance, persons with the rare 452Tyr allele showing poorer memory performance compared to His452His subjects. To investigate a...

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Identifiers

PMID: 16434999
DOI: 10.1038/sj.ejhg.5201573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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