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Article

A functional genetic variation of the 5-HT2a receptor affects human memory.

Nature neuroscience - 1 Nov 2003

de Quervain Dominique J-F, Henke Katharina, Aerni Amanda, Coluccia Daniel, Wollmer M Axel, Hock Christoph, Nitsch Roger M, Papassotiropoulos Andreas

Abstract excerpt

Human memory capacity is highly variable across individuals and is influenced by both genetic and environmental factors. A roughly 50% heritability estimate indicates that naturally occurring genetic variations have an important impact on this cognitive ability. Therefore, we investigated a functional variation of a memory-related serotonin receptor in 349 healthy young volunteers, and found 21% poorer memory...

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Identifiers

PMID: 14566344
DOI: 10.1038/nn1146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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