Article
BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population.
PloS one - 1 Jan 2014
Brooks Samantha J, Nilsson Emil K, Jacobsson Josefin A, Stein Dan J, Fredriksson Robert, Lind Lars, Schiöth Helgi B
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) links learning, memory and cognitive decline in elderly, but evidence linking BDNF allele variation, cognition and brain structural differences is lacking. METHODS: 367 elderly Swedish men (n = 181) and women (n = 186) from Prospective Investigation of the Vasculature in Uppsala seniors (PIVUS) were genotyped and the BDNF functional rs6265 SNP was further...
Topics
Join the communities discussing this publication.