BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population.

doi:10.1371/journal.pone.0082707

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population.

PloS one - 1 Jan 2014

Brooks Samantha J, Nilsson Emil K, Jacobsson Josefin A, Stein Dan J, Fredriksson Robert, Lind Lars, Schiöth Helgi B

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF) links learning, memory and cognitive decline in elderly, but evidence linking BDNF allele variation, cognition and brain structural differences is lacking. METHODS: 367 elderly Swedish men (n = 181) and women (n = 186) from Prospective Investigation of the Vasculature in Uppsala seniors (PIVUS) were genotyped and the BDNF functional rs6265 SNP was further...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cerebellum

Share to Executive Function

Share to Functional Neuroimaging

Share to Hippocampus

Share to Memory, Short-Term

Share to Organ Size

Share to Prefrontal Cortex

Source

Open in PubMed Open full text

Identifiers

PMID: 24465375
DOI: 10.1371/journal.pone.0082707
PMCID: PMC3900399

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population.PMID 24465375Read ↗

Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) gene: a gender-specific role in cognitive function during normal cognitive aging of the MEMO-Study?Semantic proximity Read ↗

The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression.Semantic proximity Read ↗

BDNF polymorphism rs6265 and hippocampal structure and memory performance in healthy control subjects.Semantic proximity Read ↗

BDNF gene polymorphisms and haplotypes in relation to cognitive performance in Polish healthy subjects.Semantic proximity Read ↗

The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology.Semantic proximity Read ↗

Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults.Semantic proximity Read ↗

BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention.Semantic proximity Read ↗

The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease.Semantic proximity Read ↗

Impact of brain-derived neurotrophic factor genetic polymorphism on cognition: A systematic review.Semantic proximity Read ↗

The Brain-Derived Neurotrophic Factor Functional Polymorphism and Hand Grip Strength Impact the Association between Brain-Derived Neurotrophic Factor Levels and Cognition in Older Adults in the United States.Semantic proximity Read ↗

The associations of the BDNF and APOE polymorphisms, hippocampal subfield volumes, and episodic memory performance across the lifespan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.