Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variations in 5-HT2A influence spatial cognitive abilities and working memory.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 Mar 2011

Gong Pingyuan, Li Jing, Wang Jian, Lei Xu, Chen Dongmei, Zhang Kejin, Zhang Wenjiang, Zhen Anyuan, Gao Xiaocai, Zhang Fuchang

Abstract excerpt

BACKGROUND: 5-hydroxytryptamine receptor 2A (5-HT2A) participates in diverse psychiatric disorders by regulating the activity of serotonin. Some previous studies have also suggested that the receptor is involved in cognitive abilities of disease groups. We hypothesize that some functional genetic variants in 5-HT2A have certain specific influences on cognitive abilities in a normal population. METHOD: To confirm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Statistics, Nonparametric
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Memory, Short-Term

Share to Neuropsychological Tests

Share to Receptor, Serotonin, 5-HT2A

Share to Sex Factors

Share to Space Perception

Source

Identifiers

PMID: 21320838
DOI: 10.1017/s0317167100011513

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variations in 5-HT2A influence spatial cognitive abilities and working memory.PMID 21320838Read ↗

A functional genetic variation of the 5-HT2a receptor affects human memory.Semantic proximity Read ↗

Association analysis of TPH2, 5-HT2A, and 5-HT6 with executive function in a young Chinese Han population.Semantic proximity Read ↗

An association study on the polymorphisms of dopaminergic genes with working memory in a healthy Chinese Han population.Semantic proximity Read ↗

No observable relationship between the 12 genes of nervous system and reasoning skill in a young Chinese Han population.Semantic proximity Read ↗

Effect of BDNF Val66Met polymorphism on digital working memory and spatial localization in a healthy Chinese Han population.Semantic proximity Read ↗

Evaluation of association of common variants in HTR1A and HTR5A with schizophrenia and executive function.Semantic proximity Read ↗

Prefrontal executive function and D1, D3, 5-HT2A and 5-HT6 receptor gene variations in healthy adults.Semantic proximity Read ↗

The His452Tyr variant of the gene encoding the 5-HT2A receptor is specifically associated with consolidation of episodic memory in humans.Semantic proximity Read ↗

Association of HTR3B gene polymorphisms with depression and its executive dysfunction: a case-control study.Semantic proximity Read ↗

Polymorphisms in the 5-HTTLPR gene mediate storage capacity of visual working memory.Semantic proximity Read ↗

The relevance of the functional 5-HT1A receptor polymorphism for attention and working memory processes during mental rotation of characters.Semantic proximity Read ↗

Age-dependent effects of the 5-hydroxytryptamine-2a-receptor polymorphism (His452Tyr) on human memory.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.