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Article

Implications of NRAS mutations in AML: a study of 2502 patients.

Blood - 15 May 2006

Bacher Ulrike, Haferlach Torsten, Schoch Claudia, Kern Wolfgang, Schnittger Susanne

Abstract excerpt

We analyzed 2502 patients with acute myeloid leukemia at diagnosis for NRAS mutations around the hot spots at codons 12, 13, and 61 and correlated the results to cytomorphology, cytogenetics, other molecular markers, and prognostic relevance of these mutations. Two hundred fifty-seven (10.3%) of 2502 patients had NRAS mutations (NRAS(mut)). Most mutations (112 of 257; 43.6%) were found at codon 12, mostly...

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Source

Identifiers

PMID: 16434492
DOI: 10.1182/blood-2005-08-3522

Genes

NRAS
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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