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[NRAS Gene Expression and Its Clinical Significance in Patients with Acute Myeloid Leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2020

Li Tian-Tian, Li Jun, Geng Ying-Hua, Zhang Feng, Liu Lin, Yang Yan-Li

Abstract excerpt

OBJECTIVE: To investigate the mutation rate and distribution of Homo sapiens neuroblastoma RAS viral oncogene homolog (NRAS) gene in the patients with acute myeloid leukemia. METHODS: The genomic DNA of bone marrow was screened by polymerase chain reaction (PCR) and sequencing for NRAS mutations. At the same time, the mutations of ASXL1, DNMT3A, TET2, CEBPA, FLT3, IDH2, NPM1 and c-KIT genes were also detected to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32027256
DOI: 10.19746/j.cnki.issn.1009-2137.2020.01.013

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