Article
[Analysis of Coexisting Gene with NRAS in Acute Myeloid Leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2022
Sheng Ye-Ping, Hua Hai-Ying, Chao Hong-Ying, Zhu Wen-Yan, Wang Zhi-Qing, Zhang Yan, Zhou Ye
Abstract excerpt
OBJECTIVE: To investigate the coexisting mutations and clinical significance of Homo sapiens neuroblastoma RAS viral oncogene homolog (NRAS) gene in acute myeloid leukemia (AML) patients. METHODS: High-throughput DNA sequencing and Sanger sequencing were used to detect 51 gene mutations. The occurrence, clinical characteristics and treatment efficacy of coexisting genes with NRAS were investigated. RESULTS: A...
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