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Article

RAS mutation analysis in a large cohort of Chinese patients with acute myeloid leukemia.

Clinical biochemistry - 1 May 2013

Yang Xiaofei, Qian Jun, Sun Aining, Lin Jiang, Xiao Gaofei, Yin Jia, Chen Suning, Wu Depei

Abstract excerpt

OBJECTIVE: We examined RAS mutational status and correlated this with presenting morphology, cytogenetics, clinical outcome and other gene aberrations in a large cohort of Chinese acute myeloid leukemia (AML) patients. DESIGNS AND METHODS: N-RAS and K-RAS were screened for mutations at hot-spot codons 12, 13 and 61 using high resolution melting analysis (HRMA) and direct DNA sequencing in 504 Chinese AML patients...

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Source

Identifiers

PMID: 23313659
DOI: 10.1016/j.clinbiochem.2012.12.022

Genes

FLT3

Variants

rs121913237
rs121434596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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