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[Clinical Significance of RAS Gene Mutations in Patients with Acute Myeloid Leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Oct 2022

Wei Ji-Feng, Qiu Hui-Ying, Chen Ze, Miao Lei, Wang Ying, Zhao Li-Dong, Cai Zhi-Mei

Abstract excerpt

OBJECTIVE: To investigate the clinical characteristics of RAS gene mutations in patients with acute myeloid leukemia (AML). METHODS: 43 myeloid gene mutations were detected using next-generation sequencing (NGS) in 180 patients with AML who were first diagnosed between May 2011 and February 2021. The molecular and clinical features of RAS gene mutations and their effects on efficacy and survival of patients were...

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PMID: 36208240
DOI: 10.19746/j.cnki.issn.1009-2137.2022.05.014

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