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Article

Association of a maternal CD14 -159 gene polymorphism with preterm premature rupture of membranes and spontaneous preterm birth in multi-fetal pregnancies.

Journal of reproductive immunology - 1 Jun 2006

Kalish Robin B, Vardhana Santosh, Normand Neil J, Gupta Meruka, Witkin Steven S

Abstract excerpt

CD14, the major receptor for bacterial lipopolysaccharide (LPS) as well as other microbial antigens, is a component of the innate immune system. We hypothesized that a single nucleotide C>T polymorphism at position -159 in the CD14 gene that results in elevated CD14 production would influence susceptibility to preterm premature rupture of membranes (PPROM) and spontaneous preterm birth (SPTB) in multi-fetal...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16427140
DOI: 10.1016/j.jri.2005.12.002

Genes

SPTB

Provenance

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