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Article

Polymorphisms of genes involved in innate immunity: association with preterm delivery.

Molecular human reproduction - 1 Dec 2004

Härtel Ch, Finas D, Ahrens P, Kattner E, Schaible Th, Müller D, Segerer H, Albrecht K, Möller J, Diedrich K, Göpel W

Abstract excerpt

An altered inflammatory activity due to functionally relevant polymorphisms of the innate immune system may influence pathways leading to labour and, therefore, impact on the frequency of preterm birth. We examined five polymorphisms of the innate immune system in a large cohort of preterm very-low-birth-weight (VLBW, n = 909) and term-born infants (n = 491) and their mothers (n = 747). The primary outcome was...

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Identifiers

PMID: 15516360
DOI: 10.1093/molehr/gah120

Genes

NOD2
TLR2
TLR4

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