Article
Toll-like receptor 2 polymorphism is associated with preterm birth.
Pediatric research - 1 Oct 2007
Krediet Tannette G, Wiertsema Selma P, Vossers Marjolein J, Hoeks Sanne B E A, Fleer André, Ruven Henk J T, Rijkers Ger T
Abstract excerpt
Evidence is increasing for a role of polymorphisms in maternal or fetal innate immune response genes in preterm birth. Toll-like receptors (TLRs) are important receptors in the innate immunity. The genotype distribution of two TLR2 single nucleotide polymorphisms (SNPs) and one TLR4 SNP were determined among 524 neonates and associated with gestational age (GA). Genomic DNA was isolated from prospectively...
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