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Article

Effects of CD14-159 C/T polymorphism on CD14 expression and the balance between proinflammatory and anti-inflammatory cytokines in whole blood culture.

Shock (Augusta, Ga.) - 1 Aug 2007

Lin Jing, Yao Yong-ming, Yu Yan, Chai Jia-ke, Huang Zhi-hong, Dong Ning, Sheng Zhi-yong

Abstract excerpt

CD14 is an important receptor of innate immunity. When CD14 is anchored by ligands to LPS, peptidoglycans, or lipoteichoic acid, it can result in either proinflammatory or anti-inflammatory responses. To determine whether CD14-159 C/T polymorphism is associated with CD14 expression and the balance of proinflammatory and anti-inflammatory responses, we studied 118 healthy ethnic Han Chinese using a whole blood...

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PMID: 17515856
DOI: 10.1097/SHK.0b013e3180341d35

Genes

TNF

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