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Article

Association between a genomic polymorphism within the CD14 locus and septic shock susceptibility and mortality rate.

Critical care medicine - 1 May 2002

Gibot Sébastien, Cariou Alain, Drouet Ludovic, Rossignol Mathias, Ripoll Laurent

Abstract excerpt

OBJECTIVE: Genetic differences in immune responses may affect susceptibility to and outcome of septic shock. CD14 seems to be an important part of the innate immune system, initiating antimicrobial response. We evaluated the frequency of a recently discovered CD14 promoter gene polymorphism (C to T transition at base pair -159) among patients with septic shock compared with those in a control group. DESIGN:...

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Share to Adrenal Hormones and Disorders
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Response and Inflammation

Share to Lipopolysaccharide Receptors

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Sepsis Diagnosis and Treatment

Share to Shock, Septic

Source

Identifiers

PMID: 12006789
DOI: 10.1097/00003246-200205000-00003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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