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Article

Toll-like receptor gene polymorphisms and preeclampsia risk: a case-control study and data synthesis.

Hypertension in pregnancy - 1 Jan 2010

Xie Fang, Hu Yuxiang, Speert David P, Turvey Stuart E, Peng Gang, Money Deborah M, Magee Laura A, von Dadelszen Peter

Abstract excerpt

BACKGROUND: Preeclampsia is a syndrome of exaggerated innate inflammatory response. It is plausible that this innate inflammation may be mediated by Toll-like receptors (TLRs). A portion of the familial susceptibility to the development of preeclampsia may be mediated by single nucleotide polymorphisms (SNPs) in the TLR gene sequences. Published reports vary in their finding an association between TLR SNPs and...

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Source

Identifiers

PMID: 20818954
DOI: 10.3109/10641950903242659

Genes

TLR2
TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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