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Article

Searching for links between endotoxin exposure and pregnancy loss: CD14 polymorphism in idiopathic recurrent miscarriage.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Oct 2003

Karhukorpi Jari, Laitinen Tarja, Karttunen Riitta

Abstract excerpt

PROBLEM: Lipopolysaccharide (LPS) (endotoxin) is a well-known inducer of abortions in mice. In addition it has been proposed that gut-derived LPS of gram-negative bacteria may play a role in triggering idiopathic recurrent miscarriage (IRM) in humans. CD14 is one of the key molecules that mediates the effects of LPS. Promoter region polymorphism (-159C/T) in the CD14 gene is functionally important by regulating...

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Source

Identifiers

PMID: 14672339
DOI: 10.1034/j.1600-0897.2003.00092.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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