Article
The differential effect of genetic variation on soluble CD14 levels in human plasma and milk.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Sept 2004
Guerra Stefano, Carla Lohman I, LeVan Tricia D, Wright Anne L, Martinez Fernando D, Halonen Marilyn
Abstract excerpt
PROBLEM: The protein CD14 is a pattern recognition receptor for bacterial lipopolysaccharide (LPS). Whether genetic variation has the same influence on soluble CD14 (sCD14) levels in human plasma and milk remains to be determined. METHOD OF STUDY: We measured sCD14 levels in plasma during pregnancy (n = 196) and in milk in the postpartum (n = 152) for women genotyped for the single nucleotide polymorphisms (SNPs)...
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