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Article

Impaired growth of pancreatic exocrine cells in transgenic mice expressing human activin betaE subunit.

Biochemical and biophysical research communications - 10 Mar 2006

Hashimoto Osamu, Ushiro Yuuki, Sekiyama Kazunari, Yamaguchi Osamu, Yoshioka Kazuki, Mutoh Ken-ichiro, Hasegawa Yoshihisa

Abstract excerpt

Activins, TGF-beta superfamily members, have multiple functions in a variety of cells and tissues. Recently, additional activin beta subunit genes, betaC and betaE, have been identified. To explore the role of activin E, we created transgenic mice overexpressing human activin betaE subunit. There were pronounced differences in the pancreata of the transgenic animals as compared with their wild-type counterparts....

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Identifiers

PMID: 16426570
DOI: 10.1016/j.bbrc.2005.12.205

Genes

PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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