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Article

EPI64B acts as a GTPase-activating protein for Rab27B in pancreatic acinar cells.

The Journal of biological chemistry - 5 Jul 2013

Hou Yanan, Chen Xuequn, Tolmachova Tatyana, Ernst Stephen A, Williams John A

Abstract excerpt

The small GTPase Rab27B localizes to the zymogen granule membranes and plays an important role in regulating protein secretion by pancreatic acinar cells, as does Rab3D. A common guanine nucleotide exchange factor (GEF) for Rab3 and Rab27 has been reported; however, the GTPase-activating protein (GAP) specific for Rab27B has not been identified. In this study, the expression in mouse pancreatic acini of two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23671284
DOI: 10.1074/jbc.M113.472134
PMCID: PMC3707656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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