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Article

Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function.

Diabetes - 1 Oct 2005

Papadopoulou Stella, Edlund Helena

Abstract excerpt

Mesenchymal-epithelial interactions are pivotal for proper pancreatic growth and development. We have earlier shown that the fibroblast growth factor (FGF) receptor 2 is expressed in pancreatic progenitor cells and that FGF10, the high-affinity ligand of the FGF receptor 2 isoform FGF receptor 2b, promotes expansion of pancreatic progenitors. The Wnt family of ligands, which signal to the Frizzled (Frz) type...

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Share to Frizzled Receptors
Share to Insulin Secretion
Share to Islets of Langerhans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, G-Protein-Coupled

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Source

Identifiers

PMID: 16186384
DOI: 10.2337/diabetes.54.10.2844

Genes

FGF10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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