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Article

Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning.

Developmental biology - 1 Jul 2014

Baumgartner Brett K, Cash Gabriela, Hansen Hillary, Ostler Shawn, Murtaugh L Charles

Abstract excerpt

Pancreatic exocrine and endocrine lineages arise from multipotent pancreatic progenitor cells (MPCs). Exploiting the mechanisms that govern expansion and differentiation of these cells could enhance efforts to generate β-cells from stem cells. Although our prior work indicates that the canonical Wnt signaling component β-catenin is required qualitatively for exocrine acinar but not endocrine development,...

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Identifiers

PMID: 24721715
DOI: 10.1016/j.ydbio.2014.03.019
PMCID: PMC4065238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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