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Article

Mathematical model for the cancer stem cell hypothesis.

Cell proliferation - 1 Feb 2006

Ganguly R, Puri I K

Abstract excerpt

Recent research on the origin of brain cancer has implicated a subpopulation of self-renewing brain cancer stem cells for malignant tumour growth. Various genes that regulate self-renewal in normal stem cells are also found in cancer stem cells. This implies that cancers can occur because of mutations in normal stem cells and early progenitor cells. A predictive mathematical model based on the cell compartment...

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Identifiers

PMID: 16426418
DOI: 10.1111/j.1365-2184.2006.00369.x
PMCID: PMC6495990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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