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Article

The origins of glioma: E Pluribus Unum?

23 Feb 2011

Abstract excerpt

Malignant glioma is among of the most devastating, and least curable, types of cancer. Since the re-emergence of the cancer stem cell hypothesis, much progress has been made towards elucidating the cellular origin of these tumors. The hypothesis that tumors are hierarchically organized, with a cancer stem cell at the top that shares defining features with somatic stem cells and provides therapeutic refractoriness...

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PMID: 21351156
DOI: 10.1002/glia.21143

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