Article
Mathematical models of cancer stem cells.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jun 2008
Michor Franziska
Abstract excerpt
Human cancers are thought to be sustained in their growth by a pathologic counterpart of normal adult stem cells: cancer stem cells. This concept was first developed in human myeloid leukemias and is today being extended to solid tumors such as breast and brain cancers. A quantitative understanding of cancer stem cells requires a mathematical framework to describe the dynamics of cancer initiation and...
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