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Article

Amino acid variants in Surfactant protein D are not associated with bronchial asthma.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Feb 2006

Krueger Marcus, Puthothu Beena, Gropp Eva, Heinze Jessica, Braun Sandra, Heinzmann Andrea

Abstract excerpt

Surfactant protein D (SFTPD) belongs to the family of collectins and is part of the innate immune system. Thereby it plays an important role in the defense of various pathogens. Besides it is involved in the development of acute and chronic inflammation of the lung. Levels of SFTPD are elevated in serum and alveolar lavage of asthmatic patients. As SFTPD binds and neutralizes common allergens like house dust...

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Source

Identifiers

PMID: 16426259
DOI: 10.1111/j.1399-3038.2005.00353.x

Genes

SFTPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Amino acid variants in Surfactant protein D are not associated with bronchial asthma.PMID 16426259Read ↗

Association of serum surfactant protein D and SFTPD gene variants with asthma in Danish children, adolescents, and young adults.Semantic proximity Read ↗

Association of Serum Surfactant Protein D and SFTPD gene variants with asthma in Danish children, adolescents and young adultsSemantic proximity Read ↗

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury.Semantic proximity Read ↗

Polymorphisms in the human surfactant protein-D (SFTPD) gene: strong evidence that serum levels of surfactant protein-D (SP-D) are genetically influenced.Semantic proximity Read ↗

Haplotypes of surfactant protein C are associated with common paediatric lung diseases.Semantic proximity Read ↗

A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D.Semantic proximity Read ↗

Surfactant protein D (SP-D) deficiency is attenuated in humanised mice expressing the Met(11)Thr short nucleotide polymorphism of SP-D: implications for surfactant metabolism in the lung.Semantic proximity Read ↗

Surfactant protein B polymorphisms are associated with severe respiratory syncytial virus infection, but not with asthma.Semantic proximity Read ↗

Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation.Semantic proximity Read ↗

Impact of a Met(11)Thr single nucleotide polymorphism of surfactant protein D on allergic airway inflammation in a murine asthma model.Semantic proximity Read ↗

Surfactant protein D alters allergic lung responses in mice and human subjects.Semantic proximity Read ↗

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