Article
Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury.
Frontiers in bioscience (Landmark edition) - 1 Jan 2012
Silveyra Patricia, Floros Joanna
Abstract excerpt
Pulmonary surfactant, a lipoprotein complex, maintains alveolar integrity and plays an important role in lung host defense, and control of inflammation. Altered inflammatory processes and surfactant dysfunction are well described events that occur in patients with acute or chronic lung disease that can develop secondary to a variety of insults. Genetic variants of surfactant proteins, including single nucleotide...
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