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Article

Polymorphisms in the human surfactant protein-D (SFTPD) gene: strong evidence that serum levels of surfactant protein-D (SP-D) are genetically influenced.

Immunogenetics - 1 Apr 2005

Heidinger Kathrin, König Inke R, Bohnert Anette, Kleinsteiber Anja, Hilgendorff Anne, Gortner Ludwig, Ziegler Andreas, Chakraborty Trinad, Bein Gregor

Abstract excerpt

The collectin surfactant protein-D (SP-D) plays a significant role in innate immunity. Epidemiological studies described associations between single nucleotide polymorphisms (SNPs) of the human gene coding surfactant protein-D (SFTPD) and infectious pulmonary diseases. Studies on twins indicated very strong genetic dependence for serum levels of SP-D. The aim of this study was to determine the genetic influence...

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Identifiers

PMID: 15700120
DOI: 10.1007/s00251-005-0775-5
PMCID: PMC7100655

Genes

SFTPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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