Article
Expression of suppressor of cytokine signaling 1 (SOCS1) gene dramatically increases in relapsing-remitting multiple sclerosis.
Journal of the neurological sciences - 15 Mar 2015
Pahlevan Kakhki Majid, Rakhshi Nahid, Heidary Masoumeh, Behmanesh Mehrdad, Nikravesh Abbas
Abstract excerpt
Suppressor of cytokine signaling 1 (SOCS1) is a key regulator of cytokines signaling and plays the most important role in the regulation of the autoimmune responses. The absence of SOCS1 leads to aberrant thymocyte development and systemic inflammation. This study was conducted to evaluate the expression level of SOCS1 mRNA in peripheral blood mononuclear cells (PBMCs) of relapsing-remitting (RR)-multiple...
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