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Article

Effect of intestinal CYP3A5 on postoperative tacrolimus trough levels in living-donor liver transplant recipients.

Pharmacogenetics and genomics - 1 Feb 2006

Uesugi Miwa, Masuda Satohiro, Katsura Toshiya, Oike Fumitaka, Takada Yasutsugu, Inui Ken-ichi

Abstract excerpt

It has been reported that hepatic and intestinal cytochrome P450 (CYP) 3A4, CYP3A5 and P-glycoprotein affect the pharmacokinetics of tacrolimus, and that these proteins are associated with the large inter-individual variation in the pharmacokinetics of this drug. We previously showed that the concentration/dose ratio of tacrolimus tended to be lower in recipients of living-donor liver transplantation (LDLT) with...

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Identifiers

PMID: 16424824
DOI: 10.1097/01.fpc.0000184953.31324.e4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of intestinal CYP3A5 on postoperative tacrolimus trough levels in living-donor liver transplant recipients.PMID 16424824Read ↗

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