Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypical expression of CYP2D6 in amerindians of tepehuano origin from Durango, Mexico.

Proceedings of the Western Pharmacology Society - 1 Jan 2005

Lares-Asseff Ismael, Sosa-Macías Martha, Elizondo-Azuela Guillermo, Flores-Pérez Carmen, Flores-Pérez Janett, Bradley-Alvarez Francisco

Abstract excerpt

Cytochrome P4502D6 (CYP2D6) shows genetic polymorphism, which is clinically important in the metabolism of drugs and other xenobiotics. Dextrometorphan (DM) has been used as a test compound to evaluate the in vivo activity of CYP2D6. Phenotypical frequencies of CYP2D6 have been determined in some populations, but little is known about them in native populations. The object of this study was to characterize the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Biotransformation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Dextromethorphan

Share to Indians, North American

Share to Mexico

Share to Nutritional Status

Share to Sex Factors

Source

Identifiers

PMID: 16416672

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypical expression of CYP2D6 in amerindians of tepehuano origin from Durango, Mexico.PMID 16416672Read ↗

Genetic polymorphism of CYP2D6 in North Indian subjects.Semantic proximity Read ↗

CYP2D6 genotype and phenotype in Amerindians of Tepehuano origin and Mestizos of Durango, Mexico.Semantic proximity Read ↗

Cytochrome P450 2D6 polymorphism in eastern Indian population.Semantic proximity Read ↗

Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan.Semantic proximity Read ↗

CYP2D6 phenotyping with dextromethorphan.Semantic proximity Read ↗

Evaluation of cytochrome P450 2D6 phenotyping in healthy adult Western Indians.Semantic proximity Read ↗

Physiologically based pharmacokinetic (PBPK) modeling of the role of CYP2D6 polymorphism for metabolic phenotyping with dextromethorphanSemantic proximity Read ↗

Frequency distribution of dextromethorphan O-demethylation in a Greek population.Semantic proximity Read ↗

Analysis of pharmacokinetic parameters for assessment of dextromethorphan metabolic phenotypes.Semantic proximity Read ↗

CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population.Semantic proximity Read ↗

Influence of CYP2D6 deletion, multiplication, -1584C-->G, 31G-->A and 2988G-->a gene polymorphisms on dextromethorphan metabolism among Mexican tepehuanos and mestizos.Semantic proximity Read ↗

The Metabolization Profile of the CYP2D6 Gene in Amerindian Populations: A Review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.