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Article

Tetranucleotide repeats in coding regions: no evidence for involvement in EMAST carcinogenesis.

Journal of molecular medicine (Berlin, Germany) - 1 Apr 2006

Kloor Matthias, Schwitalle Yvette, von Knebel Doeberitz Magnus, Wentzensen Nicolas

Abstract excerpt

Genetic instability is a hallmark of malignancy. In the majority of malignant tumors, chromosomal instability leads to major numerical and structural chromosomal aberrations. In contrast, some tumors have a deficient DNA mismatch repair system and accumulate mutations particularly in repetitive mono- and dinucleotide sequences, a phenomenon referred to as microsatellite instability (MSI). Recently, a novel...

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PMID: 16416315
DOI: 10.1007/s00109-005-0012-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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