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Article

Different types of microsatellite instability in ovarian carcinoma

29 Jun 2004

Abstract excerpt

Microsatellite instability at mono- and dinucleotide repeats is the hallmark of the hereditary non-polyposis cancer syndrome (HNPCC) and is related to deficient DNA mismatch repair. In contrast, a distinct form of microsatellite instability at selective tetranucleotide repeats (EMAST or elevated microsatellite alterations at selected tetranucleotides) was described in several non-HNPCC cancer types. EMAST is...

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PMID: 15382045
DOI: 10.1002/ijc.20455

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