Article
TP53 gene mutation status in pretreatment biopsies of oesophageal adenocarcinoma has no prognostic value.
European journal of cancer (Oxford, England : 1990) - 1 Nov 1999
Soontrapornchai P, Elsaleh H, Joseph D, Hamdorf J M, House A K, Iacopetta B
Abstract excerpt
Identification of markers which help to predict response to treatment and overall survival at the time of diagnosis would assist in the management of patients with oesophageal adenocarcinoma. In the present study we investigated the prognostic significance of mutations to the TP53 tumour suppressor gene in a large, consecutive series of oesophageal adenocarcinomas. The incidence of TP53 mutation determined by...
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