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Article

Structure and interactions at the viral surface of the envelope protein E1 of Semliki Forest virus.

Structure (London, England : 1993) - 1 Jan 2006

Roussel Alain, Lescar Julien, Vaney Marie-Christine, Wengler Gisela, Wengler Gerd, Rey Félix A

Abstract excerpt

Semliki Forest virus (SFV) is enveloped by a lipid bilayer enclosed within a glycoprotein cage made by glycoproteins E1 and E2. E1 is responsible for inducing membrane fusion, triggered by exposure to the acidic environment of the endosomes. Acidic pH induces E1/E2 dissociation, allowing E1 to interact with the target membrane, and, at the same time, to rearrange into E1 homotrimers that drive the membrane fusion...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16407067
DOI: 10.1016/j.str.2005.09.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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